Detalhe da pesquisa
1.
A phase 1 trial of 8-chloro-adenosine in relapsed/refractory acute myeloid leukemia: An evaluation of safety and pharmacokinetics.
Cancer
; 130(5): 727-739, 2024 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37897709
2.
A pilot study of lower doses of ibrutinib in patients with chronic lymphocytic leukemia.
Blood
; 132(21): 2249-2259, 2018 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30254130
3.
8-chloro-adenosine activity in FLT3-ITD acute myeloid leukemia.
J Cell Physiol
; 234(9): 16295-16303, 2019 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-30770553
4.
Phase I studies of AZD1208, a proviral integration Moloney virus kinase inhibitor in solid and haematological cancers.
Br J Cancer
; 118(11): 1425-1433, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29765150
5.
Chlorinated adenosine analogue induces AMPK and autophagy in chronic lymphocytic leukaemia cells during therapy.
Br J Haematol
; 179(2): 266-271, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28737232
6.
Transcription and translation are primary targets of Pim kinase inhibitor SGI-1776 in mantle cell lymphoma.
Blood
; 120(17): 3491-500, 2012 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22955922
7.
Mechanisms of cytotoxicity to Pim kinase inhibitor, SGI-1776, in acute myeloid leukemia.
Blood
; 118(3): 693-702, 2011 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21628411
8.
The role of p53 and p21 on 8-chloro-adenosine-induced cellular response.
Nucleosides Nucleotides Nucleic Acids
; 41(12): 1359-1374, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35227162
9.
Pirtobrutinib inhibits wild-type and mutant Bruton's tyrosine kinase-mediated signaling in chronic lymphocytic leukemia.
Blood Cancer J
; 12(5): 80, 2022 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35595730
10.
Synergy of Venetoclax and 8-Chloro-Adenosine in AML: The Interplay of rRNA Inhibition and Fatty Acid Metabolism.
Cancers (Basel)
; 14(6)2022 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35326597
11.
Blood collection methods affect cellular protein integrity: implications for clinical trial biomarkers and ZAP-70 in CLL.
Blood
; 124(7): 1192-5, 2014 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25124785
12.
Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia cells.
Blood
; 114(19): 4150-7, 2009 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-19734450
13.
The Right Dose: From Phase I to Clinical Practice.
Am Soc Clin Oncol Educ Book
; 41: 92-106, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-34010057
14.
Targeting the metabolic vulnerability of acute myeloid leukemia blasts with a combination of venetoclax and 8-chloro-adenosine.
J Hematol Oncol
; 14(1): 70, 2021 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33902674
15.
Development and characterization of prototypes for in vitro and in vivo mouse models of ibrutinib-resistant CLL.
Blood Adv
; 5(16): 3134-3146, 2021 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34424317
16.
RNA-directed agent, cordycepin, induces cell death in multiple myeloma cells.
Br J Haematol
; 140(6): 682-391, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18205859
17.
Polyadenylation inhibition by the triphosphates of deoxyadenosine analogues.
Leuk Res
; 32(10): 1573-81, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18433867
18.
Idelalisib Impacts Cell Growth through Inhibiting Translation-Regulatory Mechanisms in Mantle Cell Lymphoma.
Clin Cancer Res
; 23(1): 181-192, 2017 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27342398
19.
Protein profiling identifies mTOR pathway modulation and cytostatic effects of Pim kinase inhibitor, AZD1208, in acute myeloid leukemia.
Leuk Lymphoma
; 57(12): 2863-2873, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27054578
20.
Mcl-1: the 1 in CLL.
Blood
; 112(9): 3538-40, 2008 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18948586